Tonight Cobi Smith will give her final PhD presentation, sharing practical examples from her work internationally. Her thesis investigates how and why local deliberations and decisions about global scientific issues can have impact. A core argument is that distinctions others have drawn between governance and values in developed versus developing countries detract from effective global governance and meaningful local participation in decision-making. Taking a universal, interdependent human rights-based approach to governing global scientific issues is more constructive than framing nation-states as the core decision-makers. Likewise, value frames that give researchers or corporations the most agency in decision-making about science and technological development result in conflict. Decision-making at the level of international law or market regulation can lose sight of the people laws are designed to protect and markets to serve. This is why global goverance needs to explicitly draw on local deliberations and decision-making, for legitimacy and accountability.